Prostate Cancer Hormone
prostate is a walnut sized gland which is situated in the lower part of the intestine. It plays major role in
the body which makes it indispensable to men life. But sometimes it can be affected by diseases, ranging from
minor to serious conditions such as prostate cancer. Prostate cancer is a common and serious type of cancer that
strikes men, mainly men over the age of fifty (50). The disease occurs in the prostate gland when a group of cells divide and grow
uncontrollably to become malignant. Once the cancerous cells are found in the gland, treatment is required to
prevent complications or death. There are many types of treatment for prostate cancer. Therapy (ies)
adopted largely depend on the age of the patient and the stage of the cancer at diagnosis. Some of the common
treatments for prostate cancer include surgery, radiation therapy, hormonal therapy or combination of two or
suffering from prostate cancer is given hormones that suppress androgen, a male hormone. These androgens are produced in the testicles and are responsible for causing
the prostate cancer. They are also the reason for the rapid and
unleashed growth of cancer cells. The progression of the cancer cells can be reduced if the androgen levels are
lowered. It is important to understand here that hormonal therapy only prevents the cancer cells from rapid
multiplication and does not cures it completely. It has to be
combined with other therapies to completely remove the cancer from the patient’s body.
Hormone Therapy can involve surgical
therapy and the use of medications. Common techniques and drugs used to reduce androgen levels
Orchiectomy: This method involves surgical
intervention to remove the testicles of the diseased person. These testicles are responsible for the secretion
of the androgen which is needed by prostate cancer cells to continue growing; hence their removal will slow down
the process of cancer growth. Common complications or side effects of orchiectomy include:
Analogue (GnRH analogue): Also called
luteinizing hormone releasing hormone agonist (LHRH agonist) or LHRH
analogue, this method consists of injecting the LH RH analogues in small portions under the skin.
Normally these injections are given every one, three, four, six, or twelve months. Lupron, Eligard, Viadur, Trelstar and
Zoladex are the most commonly used LH RH analogues. This method is
preferred over orchiectomy.
Estrogen: The estrogen hormone is injected inside the patient. However not many prostate cancer
victims prefer this treatment as estrogen is a female hormone which can alter the masculine personality of the
person to a feminine one.
Anti androgens are pills that bring down the action of the
androgens. The commonly used anti androgens are casodex, Nilandron (Nilutamide) and eulexin. This treatment
is normally combined with orchiectomy.
Hormone Therapy Side
Therapy can be very useful in combatting prostate malignancy, but it comes with several adverse
reactions. Some common side effects in case of LH RH and
The side effects of Anti
Most of these side
effects can be cured or reduced soon after the hormone therapy is over.
Hormonal Therapy in Prostate Cancer
Despite being a
beneficial and favorable treatment for prostate cancer patients, hormone therapy has few limitations which